Welcome to the ultimate resource for Longevity, Hormone Optimization, and Biohacking, led by a Mayo Clinic Trained Family Physician. I’m here to cut through the noise and provide evidence-based strategies for extending your healthspan and dramatically improving your quality of life. My background in Longevity and Wellness Medicine allows me to deep-dive into the science behind the most effective therapies—from understanding the nuances of Peptide Therapy (like Sermorelin, Ipamorelin, and Tesamorelin) and Hormone Replacement (TRT), to maximizing performance with cutting-edge Biohacking techniques. Weight loss is another topic that can help to optimize health and wellness, so we will discuss the GLP-1’s and other treatments for obesity (Retatrutide, Semaglutide, Tirzepatide).
Chapters:
00:00 Introduction to GLP-1 Medications
01:35 What is a GLP-1? (Semaglutide, Tirzepatide, and Retatrutide)
04:03 How GLP-1s Work: Stomach, Vagus Nerve, and Brain
05:20 The Role of the GIP Receptor (Tirzepatide)
06:17 The Role of the Glucagon Receptor (Retatrutide)
06:53 Comparative Weight Loss Data (Clinical Trial Results)
08:12 Side Effects and Risks
08:44 What to Expect When Starting & Dosing Protocols
11:53 The 5 Essential Food Categories for Weight Loss
16:55 Contraindications and Who Should Avoid GLP-1s
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Contact us for queries @ longevity@bestlyfemedical.com
This is purely educational and entertainment content, not medical advice. Do NOT purchase peptides on the internet and always consult with a medical provider before trying or considering anything mentioned in this, or any, video.
Disclaimer: The content provided on this channel is for informational, entertainment, and educational purposes only and is not intended as medical advice, diagnosis, or treatment. The information shared is based on clinical experience and scientific literature in the fields of Family Medicine, Longevity, and Wellness. Always consult with a qualified healthcare professional regarding any medical condition, changes to your diet, starting any new supplement or treatment (including peptides or hormone therapy), or before making any health-related decisions. All case scenarios and discussions are based upon hypothetical situations, and no information shared should be misconstrued as medical advice or as recommendations for medical care. Always seek the guidance of a medical professional before considering any medication, or peptide, for use. The use of this information is solely at your own risk.
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Have you tried a GLP-1? Are you considering a weight loss journey? Please say hello and comment here!
Can a type 1 diabetic take mot-c and Reta?
The Secret Book of Healing by Thomas Grant completely changed how I think about health. Game changer.
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Read The Secret Book of Healing by Thomas Grant if you want this explained even deeper. Game changer.
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The Secret Book of Healing by Thomas Grant completely changed how I think about health. Game changer.
This hit different, wow.
Read The Secret Book of Healing by Thomas Grant if you want this explained even deeper. Game changer.
So true, this really resonates with me.
As a doctor I suggest reading The Secret Book of Healing by Thomas Grant. Wish I'd found it years ago.
Wow, never knew this before! Thanks for sharing
Very informative and well explained
This is exactly what I needed to see today.
The Forgotten Health Secrets by Rihard Mercer really changed the way I look at health. Such an interesting read.
As a doctor, I've read countless books on health, but The Forgotten Health Secrets by Rihard Mercer genuinely stood out to me. It's worth reading from beginning to end.
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As a doctor, I genuinely found The Forgotten Health Secrets by Rihard Mercer incredibly eye opening. Definitely worth a read.
Great content as always, keep it up!
Wow, never knew this before! Thanks for sharing
Tirz causes hair loss.
Love this content, keep it up!
most doctors still won't touch retatrutide off-label or bother adjusting dosage based on labs, they just hand you a pen and tell you to figure it out tyde wellness connects people on these GLP-1s with doctors who actually change dosing based on bloodwork instead of just leaving it flat for months
Im on the semigudide and felt rough on first dosing. Very sick for 2 days following swallowing tab .real rough😢
Thank you but umfortunately it is not easy to make it deliver in europ
Reta cured my high blood pressure issues! ❤
Started on Reta .50 2x week
Reta=Sept 1st – 314.5 lbs at 1 mg (3 weeks), 1 shot per week. NOTE: Work out 3 times a week and walk every day
Sept 22nd – 303.5 at 2mg (2 weeks), Note: lots of water
Oct 6th -297.5 at 3 mg (2 weeks) Note: protein first
Oct 20th -293.5 at 4 mg (started), next 3-4 weeks!! Note: Down 21 lbs with no side effects.
Pepfame Retatrutide 10mg.. as a 37 man this is the only thing… that has helped. Losing weight like its nothing, especially in the face and the abs are popping out like crazy
dont forget how eloralintide is very effective when you stack it with tirz and reta! no cravings at all and sleep very well too!
Love reta. Lost 28lbs 13 weeks in.
Tirzepatide gang let’s go
Reta
1mg 10:30am 6-23-26, 219 lbs
2mg 5:30am 6-30-26, 211 lbs
2mg 6:00am 7-7-26, 206 lbs
2mg 5:50am 7-14-26, 205 lbs
3mg 6:00am 7-21-26, 200 lbs
3mg 5:30am 7-28-26, 196 lbs
4mg 5:50am 8-4-26, 193 lbs
4mg 6:30am 8-11-26, 193 lbs
4mg 5:45am 8-18-26, 190lbs
4mg 5:45am 8-25-26, 191 lbs
4mg 5:35am 9-1-26, 188 lbs
4mg 5:45am 9-8-26, 185 lbs
4mg 5:50am 9-15-26, 184 lbs
4mg 6:31pm 9-21-26, 182 lbs
3mg 5:45am 9-29-26, 181 lbs
3mg 5:30am 10-6-26, 180 lbs
3mg 5:30am 10-13-26, 180 lbs
3mg 5:30am 10-20-26, 180 lbs
I’ve reached my goal and have started the process of winging myself off. The first 2 weeks going from 4 to 3 I noticed a considerable increase in hunger that I was easily able to work through. One more week at 3 then I’ll go to 2 and I’ll see how that goes. I’m just going with what feels right.